The game is a shooter. Pulling the left trigger causes the over-the-shoulder view to zoom in, allowing for more precise aiming. Clicking on the right analog stick causes the game to switch to a camera, which lets the player look down the iron sights. Some cover can be partially destroyed, forcing players to seek other hiding spots. While taking cover, players can be suppressed by machine gun fire, which takes the effect of narrowing and shaking the player's field of vision, making it harder to return firre.
A new feature in the series is which allows the Ghosts to become partially invisible. In the game, it is explained that the processing power doesn't exist yet for the camoufflage to keep up with quick movements, so it is only active when the player moves slowly. It's enabled automatically when the player crouches, and disengages when running, firing or taking damage.
- The game opens in the year 2024 with a four-Man Ghost Recon team Predator, led by Joe Ramirez,
- Upon inspection of the convoy vehicles, is remotely detonated, killing the team.
- Investigating the cause and tracking down the source of the grenade is tasked to another Ghost team call-signed Hunter
- The team ships out from , under the supervision of Scott Mitchell.