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Orthomolecular & No Flush Inositol Hexanicotinate (IHN) 90 Capsules

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Iron Bisglycinate 60 Capsules

Iron Bisglycinate Supplement Our dietary supplement Iron Bisglycinate offers a simple way of increasing your iron intake. The body needs iron in order to function properly. This trace element participates in a number of mechanisms of action including the formation of new cells, hormones and neurotransmitters. What are the benefits associated with Iron Bisglycinate supplement? Iron Bisglycinate is formulated from a specific form of iron - iron reacted with glycine to form a chelate called ferrous bisglycinate. This has the advantage of being an anti-fatigue form of iron with excellent bioavailability due to its low molecular weight. It is thus easily absorbed by the gut, making it bioavailable within the body. In addition, ferrous bisglycinate is a stable form of iron. Having no ion charge, it does not interact with other nutrients in the digestive system and is therefore well-absorbed by the body. Iron also plays an essential role in enabling red blood cells to transport oxygen from the respiratory system to the body's tissues. This is why a lack of iron can be damaging to our health and why supplementation is sometimes necessary - particularly since serious iron deficiency can impair cognitive development and cause iron-deficiency anemia - a condition in which a lack of iron results in a reduction in red blood cells leading to poor oxygenation of the body. Why is iron supplementation important? Iron deficiency has been a significant public health issue for several years. The World Health Organisation (WHO) estimates that 1.3 billion people suffer from iron deficiency anemia. Of the many potential causes, the most common is inadequate intake, or poor absorption, of dietary iron. The body does not produce iron and it must therefore be provided by the diet: Iron is found mainly in animal-source foods, hence the need for vegetarians and vegans to find alternative sources.A lack of dietary iron is also common among women, particularly during pregnancy. Indeed, women of reproductive age have increased iron requirements because their levels are more subject to depletion. It is estimated that iron levels may fall by up to 25% during menstruation and pregnancy.Iron deficiency may be caused by other factors such as intestinal malabsorption, gastrointestinal bleeding or gastric surgery.Inadequate iron intake resulting in deficiency can lead to health complications. Symptoms include: fatigue; muscle weakness; lack of stamina; light-headedness; loss of libido; sluggish immune system.These symptoms are associated with poor oxygenation of the body, both in muscles and in several organs such as the brain, heart, kidneys and lungs.Scientists have also observed that a lack of iron can lead to learning difficulties and poor concentration. This is why supplementing with iron may help improve cognitive ability and prevent heart failure. The ferrous bisglycinate used in our supplement is a safer, more effective form than either ferrous sulfatee, iron citrate or iron D-gluconate, all of which can produce side-effects such as gastric problems. Studies on ferrous bisglycinate, on the other hand, have revealed no negative side-effects on the stomach wall or intestines. The benefits of this type of iron are now available to buy at Supersmart as a dietary supplement in the form of 25g capsules, with a suggested dose of three capsules a day for optimal iron intake. Buy Iron Bisglycinate to improve your iron intake.Key FeaturesHelps with anemia and iron deficiency.A lack of dietary iron is also common among women, particularly during pregnancy. Indeed, women of reproductive age have increased iron requirements because their levels are more subject to depletion. It is estimated that iron levels may fall by up to 25% during menstruation and pregnancy.Iron deficiency may be caused by other factors such as intestinal malabsorption, gastrointestinal bleeding or gastric surgery.Associated with improvements in cognitive ability.Meets the increased needs of iron for vegetariansIron is found mainly in animal-source foods, hence the need for vegetarians and vegans to find alternative sources.

SuperFolate 400 Mcg 120 Tablets Folic Acidd

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydrofolic acidd. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of? Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acidd, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acidd because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acidd, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acidd into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acidd are ingested over long periods. Indeed, long-term supplementation with standard folic acidd-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake. Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acidd because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acidd. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acidd. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acidd (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

PQQ & Q10 (CoQ10) Mitochondria Up To 20% Aging Cells 30Caps

This PQQ & CoQ10 supplement improves antioxidant status and mitochondrial health via complementary mechanisms by providing multi-faceted support for cardiovascular and cerebral function. It also improves mental condition and quality of life in elderly patients and may be beneficial in delaying or preventing cognitive decline in middle-aged individuals. What are the benefits associated with PQQ & Q10 capsules? This new dietary supplement offers the synergistic benefits of pyrroloquinoline quinone (PQQ) and co-enzyme Q10 (CoQ10). Extensively studied in recent years, these two compounds offer significant antioxidant potency. They are thus able to combat oxidative stress - the result of attacks on cells by highly reactive species. The best-known of these are free radicals which contribute to premature aging of cells as well as the development of certain age-related disorders such as cognitive impairment. The good news is that antioxidants are available which can fight the effects of free radicals and protect cognitive function, such as PQQ and CoQ10. PQQ PQQ - or to give it its scientific name, pyrroloquinoline quinone - is one of the most powerful antioxidants currently known. It has the advantage of having good molecular stability which makes it highly effective at fighting oxidative stress. Its antioxidant activity is particularly beneficial for protecting mitochondria, the cell structures essential for energy production. In addition to this protective role, it promotes new mitochondrial growth: It's an ultra-powerful antioxidant, up to 5,000 times more effective than vitamin C.It's the only nutrient capable of generating new mitochondria - up to 20% more, in existing - even aging - cells.It uniquely ensures protection for mitochondrial DNA, which is particularly exposed and vulnerable to oxidative stress. Coenzyme Q10 Coenzyme Q10 features in the composition of a number of anti-aging formulations. In helping to protect the body against free radicals, coenzyme Q10 helps prevent premature aging of the cells and the onset of certain age-related symptoms. In addition, this powerful antioxidant works within the mitochondria for the production of adenosine triphosphate (ATP). The main energy source for numerous cellular functions, ATP is essential in order for the body to function properly. Despite this critical role, the body's ATP reserves are very low and need to be constantly renewed, hence the importance of coenzyme Q10 for maintaining vital and cognitive functions. Why combine PQQ and Q10? Often recommended individually, PQQ and CoQ10 are combined in this supplement to take advantage of their synergistic effects. Indeed, recent research has shown that combining them in this way may strengthen their protective role against oxidative stress. These studies suggest that their antioxidant effects may be particularly enhanced in the cardiovascular and nervous systems. As a result, PQQ and CoQ10 are today associated with protecting the heart, red blood cells and brain, as well as preventing age-related problems such as memory loss and concentration deficit. The suggested dose for this PQQ & CoQ10 supplement is two capsules a day. Other powerful antioxidants are also available at Supersmart for fighting age-related cellular damage such as resveratrol, the natural antioxidant found in grapes and red wine. For optimal efficacy, this protective compound can also be combined with other antioxidants such as in the synergistic formulation Resveratrol Synergy. Buy PQQ & Q10 to help fight cellular aging.Key FeaturesProtects against the oxidative stress responsible for aging.May fight age-related decline in cognitive function (attention, memory).Contains key nutrients for protecting the heart, brain and red blood cells.THIS PQQ AND COQ10 supplement improves antioxidant status and mitochondrial health via complementary mechanismsWHAT ARE THE BENEFITS? It provides multi-faceted support for cardiovascular and cerebral function. It also improves mental condition and quality of life in elderly patients and may be beneficial in delaying or preventing cognitive decline in middle-aged individualsHOW TO TAKE IT? Take 1 or 2 capsules a day, preferably with a meal containing a little fat.CONTAIN: Pyrroloquinoline quinone, Coenzyme Q10. Other ingredients : Acacia Gum.

Super Folate Supplement - Folic Acidd 400 Mcg Per Day

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydro folic acidd. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of?Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acidd because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acid. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acidd, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acidd because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acidd, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acidd into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acidd are ingested over long periods. Indeed, long-term supplementation with standard folic acidd-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acidd. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acid (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

Astragaloside IV 98% 100Mg Per Day Astragalus Root Extract - Antioxidant & Anti Inflammatory

Astragaloside IV Supplement - Astragalus Extract with Anti-Ageing Properties Astragaloside IV is an anti-ageing supplement in vegetarian capsules with several beneficial properties, particularly immunostimulant, anti-inflammatory, antioxidant and anti-glycation. Its exceptional properties are due to astragaloside's specific ability to activate telomerase, thus slowing down the shortening of telomeres, and extending cell lifespan. Shortening of telomeres is associated with cellular ageing and the development of age-related diseases. How is Astragaloside IV obtained? Astragaloside IV is present in minute amounts in the root of Astragalus (Astragalus membranaceus), a plant particularly valued in traditional Chinese medicine. Through a highly complex and expensive process, it is extracted and concentrated in order to obtain an active amount. Commercially available products sold in the form of powder or astragalus extract do not contain detectable amounts of Astragaloside IV. Astragalus root has been prescribed for centuries as a tonic, as well as to treat a wide range of diseases, to prevent weakness in patients and to protect them against infection. What are the benefits associated with Astragaloside IV capsules? Astragalus root contains, amongst others, a series of cycloartane glycosides called astragalosides I to VII. The most widely studied of these, in Chinese and European research centres, is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV have the following properties: Immunostimulant: acting through a number of different pathways, especially by increasing the number of stem cells in the spinal cord and lymphatic tissue and encouraging them to develop into active immune cells and by stimulating the production of immunoglobulins and macrophages;Anti-inflammatory: as shown in certain animal models. The ability of astragaloside IV to stem inflammation of the airways in chronic asthma has been reported in studies on mice.Antibacterial: as demonstrated by in vitro studies on Shigella dysenteriae, Streptococcus haemolyticus, Diplococcus pneumoniae and Staphylococcus aureus.Antiviral: inhibiting replication of certain viruses such as coxsackie, responsible for myocarditis (inflammation of the heart muscle). In both animal and human studies, they were shown to stimulate endogenous interferon production and to maximise its effect on viral infections.Antioxidant: inhibiting lipid peroxidation by 40% in vitro. These antioxidant properties may go some way to explaining the cardio- and neuroprotective effects of astragalus and astragaloside IV.Cardioprotective: with studies highlighting health benefits for patients with congestive cardiac insufficiency and angina pectoris. Astragalus extracts have a cardiotonic effect.Neuroprotective: in traditional Chinese medicine, astragalus root extract is used to treat neurodegenerative diseases. One study demonstrated the capacity of astragaloside IV to protect dopaminergic neurons (progressive degeneration of dopaminergic neurons leads to the development of Parkinson's disease). Telomere shortening is currently one of the most widely studied areas of anti-ageing medicine. Along with astragaloside IV, there's a number of natural active principles available to buy at Supersmart, that have been identified for their ability to protect telomeres or stimulate telomerase. Two such ingredients are cycloastragenol and resveratrol. Other beneficial compounds, such as vitamins C and E, carnosine and several natural antioxidants, have also been included in the enhanced formulation Telomeres Maintenance Formula. The shortest telomeres have been observed in octogenarians. Research also suggests that individuals aged 60 or older with the shortest telomers appear to be at significantly higher risk of death from infectious disease or heart attacks. Conversely, studies have shown that stimulating telomerase may significantly increase cell lifespan. Buy Astragaloside IV to fight cellular ageing.Key FeaturesHas antioxidant, immune-stimulant and anti-inflammatory properties.Recognised for its specific ability to activate telomerase, slowing down the shortening of telomeres, and extending cell lifespan.Fights cellular ageing and the development of age-related diseases. WHAT IS IT? Astragaloside IV may be an anti-aging supplement in vegetarian capsules with several beneficial properties (immunostimulant, anti-inflammatory, antioxidant) due to astragaloside's specific ability to activate telomerase. WHAT ARE THE BENEFITS? The most widely studied in Chinese and European research centers is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV may have the properties to be an immunostimulant, anti-inflammatory, antioxidant. HOW TO TAKE IT? Take 2 capules a day. CONTAIN: Astragaloside IV 98% - Other ingredients : Acacia gum, rice flour.

Conntrated Vitamin B9 - Folic Acid 400 Mcg 120Tab

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydrofolic acid. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of? Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acid, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acid because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acid, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acid into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acid are ingested over long periods. Indeed, long-term supplementation with standard folic acid-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake. Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acid because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acid. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acid. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acid (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

Vitamin E Tocotrienols. 60 Softgel

Our Annatto Tocotrienols supplement is formulated from an extract of Bixa orellana. Also known as roucou, urucum, achiote, and simply annattos, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for several health benefits. These seed-filled fruits have been used for many years in traditional medicine, where they have mostly been used for insect bites and protecting the skin against the sun's rays. But Bixa Orellana fruits offer considerably more benefits than that. They are rich in carotenoids, such as beta-carotene, a powerful natural antioxidant, and contain a number of trace elements, including selenium, magnesium, and calcium. They also have a high content of a specific form of Vitamin E called tocotrienols, so it also works as a healthy natural Vitamin E supplement. Annatto Tocotrienols Benefits Given its essential role in the body, Vitamin E must be ingested in sufficient amounts. While it is present in plants, such as vegetable oils and nuts, it can be easy not to get enough of it. In fact, there is not just one form of Vitamin E, but eight, that are grouped into tocopherols and tocotrienols. There are fewer dietary sources of tocotrienols, specifically, which is why our Annatto Tocotrienols supplement has been formulated from natural tocotrienols extracted from the fruit of Bixa orellana. Our formulation offers 90% delta-tocotrienols and 10% gamma-tocotrienols. Like all vitamins, Vitamin E has a number of roles within the body. It also has many properties in common with other vitamins, such as natural antioxidant power, which it shares with its well-known counterpart, Vitamin C. Annatto Tocotrienols benefits may include: Fighting aging of the cells and skin by protecting cell membranes, such as those in the skin.Combating coronary disease, a type of cardiovascular disease caused by circulation problems, by protecting the red blood cells responsible for healthy oxygenation of the body.Combating the onset of cardiovascular events, such as heart attacks and strokes, by protecting low-density lipoproteins (LDLs) — particles known for their key role in transporting cholesterol in the bloodstream. What does research show about Bixa Orellana Seed Extract? Despite the many studies conducted on tocotrienols, their mechanism of action within the body has yet to be fully explained. Research suggests, however, that these forms of natural Vitamin E may offer significant therapeutic potential. In fact, studies show that tocotrienols may: Positively influence cholesterol metabolism due to an inhibitory effect on the enzyme HMG-CoA, which reduces the amount of cholesterol produced by the liver.Potentially reduce levels of bad LDL-cholesterol and increase levels of good HDL-cholesterol.Promote a balanced lipid profile, helping to combat the build-up of atheromatous plaque in the arteries and maintain normal blood levels of glucose and triglycerides.Have a diuretic effect — i.e. promote the production of urine.Combat the risk of developing a Vitamin E deficiency. In essence, Bixa Orellana seed extract offers significant therapeutic potential. In order to create a high-quality supplement, Annatto Tocotrienols has been formulated from natural extracts and is produced in the form of softgels. Each capsule contains 100 mg of annatto extract (Bixa Orellana) standardized to 50% tocotrienols. In addition to this natural tocotrienols supplement, you can buy our Gamma E Tocopherols product to increase intake of other forms of Vitamin E. Annatto Tocotrienols Side Effects Are Annatto Tocotrienols supplements safe to consume? Taking Annatto capsules from the Roucou plant is generally safe for anyone looking to improve their overall health. Annatto or Vitamin E will rarely lead to side effects, but it is always important to research all the pros and cons in order to ensure it's good for your own well being. Most instances of side effects acquired through taking a supplement containing Bixa Orellana occur due to not following the recommended serving size. Side effects from supplements are always more likely when taking too much, and exceeding the serving size won't enhance the effects. If you are taking any existing prescription medications for chronic illnesses, it is strongly recommended to schedule a visit to your doctor. They will be able to analyze your medical history to determine whether Annatto Tocotrienols will cause any adverse drug interactions. You will find plenty of online research materials relating to Annatto extract, the Achiote plant, and Bixa Orellana seed extract that detail potential side effects and any other associated risks. Some people also like to speak to others about their experiences with Annatto Tocotrienols' side effects. Consulting with others — either in real life or online via forums — will give you a better idea of the benefits and drawbacks of adding this supplement to your daily regimen. When taking any supplement, carefully monitor the effects on your mind and body. If you experience any side effects, stop taking your Annatto supplement immediately and consult your doctor. It is common for people taking prescription medications and other supplements to experience adverse side effects. Speaking to your primary care physician can shed light on why it may be happening and how to take an Annatto Vitamin E supplement safely. Take control of your health and always consume dietary supplements responsibly.Key FeaturesHas a high content of a specific form of Vitamin E called tocotrienols.Supports healthy cholesterol metabolism.Powerful natural antioxidant.WHAT IS IT? Our dietary supplement Annatto Tocotrienols is formulated from an extract of Bixa orellana. Also known as roucou, urucum and achiote, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for their health benefits. WHY TAKE IT? Known as annattos, these seed-filled fruits have been used for many years in traditional medicine, where they may be recommended for treating insect bites or for protecting against the sun's rays.HOW TO TAKE IT? Take 2 softgels a day. CONTAIN: DeltaGold, Annato extract (Bixa orellana) standardized to 50% tocotrienols - Other ingredients: rice bran oil

Double Strength Glutathione - 1000mg X 60 Tablets

The king of endogenous antioxidants in its reduced form Contains 1000mg of reduced glutathione per capsule.Endogenous production declines with age.Naturally present in the body.Can be combined with vitamin C to combat oxidative stress.Reduced Glutathione - Endogenous Antioxidant in a Reduced StateReduced Glutathione is a dietary supplement containing 500mg reduced glutathione per capsule, a powerful dose which allows significant amounts of glutathione to reach the body's cells. What exactly is reduced glutathione? Glutathione is a molecule composed of 3 peptides: glutamic acid, cysteine and glycine. It is present at relatively high concentrations in every cell in the body: unlike vitamins, glutathione is a molecule produced naturally by the body. However, this production declines with age, sometimes to the extent where it is insufficient to properly protect the body. Why take glutathione in its reduced form? Once in the gut, glutathione molecules are captured by enzymes called gamma-glutamyl transpeptidases, which convert them into compounds that are relatively useless. Some molecules, however, escape this fate: they cross the intestinal barrier before being oxidised by these enzymes and thus reach the bloodstream in a fully-functioning state. To maximise the amount of these ‘escapee' molecules, one strategy is to increase the body's uptake of reduced glutathione (1). Offering 500mg per capsule, our supplement Reduced Glutathione is the perfect way to do this. Another way is to bind the glutathione to a particular molecular group in order to protect it from this fate. This is a more discerning approach which we also offer with our supplement S-Acetyl Glutathione, a reduced glutathione supplement in an acetylated form. Can reduced glutathione reach the brain? The ability of reduced glutathione to reach cells in the brain is hampered by the blood-brain barrier (3). However, natural glutathione production in brain cells relies on recycling its constituents, and as a result, an increase in glutathione in the bloodstream can still promote this process. Why is the brain more vulnerable to oxidative stress? There are a number of reasons why the brain is more vulnerable to oxidative stress: the brain contains a large amount of unsaturated fatty acids which are highly oxidisable and potentially very damaging to neighbouring cells;brain cells consume more than 20% of the oxygen used by the body, but represent just 2% of body mass: significant numbers of reactive oxygen species (ROS) are thus generated in the brain;the brain is rich in iron which is essential for DNA synthesis but which is involved in lipid peroxidation;there are fewer antioxidant enzymes such as endogenous glutathione in the brain than in other organs. These factors are all exacerbated by age and clearly play a part in the development of neurodegenerative diseases. How should Reduced Glutathione be taken? We recommend taking one or two tablets a day, as advised by your therapist, with a meal. To boost the effects of glutathione, we'd also recommend combining it with one of the following: Vitamin C, which helps fight oxidative stress; Vitamin E , a powerful antioxidant which helps protect cells; Flavonoids, a group of more than 6000 natural compounds which exert myriad biological activities;Zinc, an indirect antioxidant which acts as a stabiliser of superoxide dismutase; Superoxide dismutase itself, an essential element in the mechanism of free radical elimination.Key FeaturesContains 1000mg of reduced glutathione per capsule.Endogenous production declines with age.Naturally present in the body.Can be combined with vitamin C to combat oxidative stress.

Inositol Hexanicotinate (IHN) 90 Capsules Orthomolecular & No Flush

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Annatto Tocotrienols 60 Softgel

Our Annatto Tocotrienols supplement is formulated from an extract of Bixa orellana. Also known as roucou, urucum, achiote, and simply annattos, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for several health benefits. These seed-filled fruits have been used for many years in traditional medicine, where they have mostly been used for insect bites and protecting the skin against the sun's rays. But Bixa Orellana fruits offer considerably more benefits than that. They are rich in carotenoids, such as beta-carotene, a powerful natural antioxidant, and contain a number of trace elements, including selenium, magnesium, and calcium. They also have a high content of a specific form of Vitamin E called tocotrienols, so it also works as a healthy natural Vitamin E supplement. Annatto Tocotrienols Benefits Given its essential role in the body, Vitamin E must be ingested in sufficient amounts. While it is present in plants, such as vegetable oils and nuts, it can be easy not to get enough of it. In fact, there is not just one form of Vitamin E, but eight, that are grouped into tocopherols and tocotrienols. There are fewer dietary sources of tocotrienols, specifically, which is why our Annatto Tocotrienols supplement has been formulated from natural tocotrienols extracted from the fruit of Bixa orellana. Our formulation offers 90% delta-tocotrienols and 10% gamma-tocotrienols. Like all vitamins, Vitamin E has a number of roles within the body. It also has many properties in common with other vitamins, such as natural antioxidant power, which it shares with its well-known counterpart, Vitamin C. Annatto Tocotrienols benefits may include: Fighting aging of the cells and skin by protecting cell membranes, such as those in the skin.Combating coronary disease, a type of cardiovascular disease caused by circulation problems, by protecting the red blood cells responsible for healthy oxygenation of the body.Combating the onset of cardiovascular events, such as heart attacks and strokes, by protecting low-density lipoproteins (LDLs) — particles known for their key role in transporting cholesterol in the bloodstream. What does research show about Bixa Orellana Seed Extract? Despite the many studies conducted on tocotrienols, their mechanism of action within the body has yet to be fully explained. Research suggests, however, that these forms of natural Vitamin E may offer significant therapeutic potential. In fact, studies show that tocotrienols may: Positively influence cholesterol metabolism due to an inhibitory effect on the enzyme HMG-CoA, which reduces the amount of cholesterol produced by the liver.Potentially reduce levels of bad LDL-cholesterol and increase levels of good HDL-cholesterol.Promote a balanced lipid profile, helping to combat the build-up of atheromatous plaque in the arteries and maintain normal blood levels of glucose and triglycerides.Have a diuretic effect — i.e. promote the production of urine.Combat the risk of developing a Vitamin E deficiency. In essence, Bixa Orellana seed extract offers significant therapeutic potential. In order to create a high-quality supplement, Annatto Tocotrienols has been formulated from natural extracts and is produced in the form of softgels. Each capsule contains 100 mg of annatto extract (Bixa Orellana) standardized to 50% tocotrienols. In addition to this natural tocotrienols supplement, you can buy our Gamma E Tocopherols product to increase intake of other forms of Vitamin E. Annatto Tocotrienols Side Effects Are Annatto Tocotrienols supplements safe to consume? Taking Annatto capsules from the Roucou plant is generally safe for anyone looking to improve their overall health. Annatto or Vitamin E will rarely lead to side effects, but it is always important to research all the pros and cons in order to ensure it's good for your own well being. Most instances of side effects acquired through taking a supplement containing Bixa Orellana occur due to not following the recommended serving size. Side effects from supplements are always more likely when taking too much, and exceeding the serving size won't enhance the effects. If you are taking any existing prescription medications for chronic illnesses, it is strongly recommended to schedule a visit to your doctor. They will be able to analyze your medical history to determine whether Annatto Tocotrienols will cause any adverse drug interactions. You will find plenty of online research materials relating to Annatto extract, the Achiote plant, and Bixa Orellana seed extract that detail potential side effects and any other associated risks. Some people also like to speak to others about their experiences with Annatto Tocotrienols' side effects. Consulting with others — either in real life or online via forums — will give you a better idea of the benefits and drawbacks of adding this supplement to your daily regimen. When taking any supplement, carefully monitor the effects on your mind and body. If you experience any side effects, stop taking your Annatto supplement immediately and consult your doctor. It is common for people taking prescription medications and other supplements to experience adverse side effects. Speaking to your primary care physician can shed light on why it may be happening and how to take an Annatto Vitamin E supplement safely. Take control of your health and always consume dietary supplements responsibly.Key FeaturesHas a high content of a specific form of Vitamin E called tocotrienols.Supports healthy cholesterol metabolism.Powerful natural antioxidant.WHAT IS IT? Our dietary supplement Annatto Tocotrienols is formulated from an extract of Bixa orellana. Also known as roucou, urucum and achiote, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for their health benefits. WHY TAKE IT? Known as annattos, these seed-filled fruits have been used for many years in traditional medicine, where they may be recommended for treating insect bites or for protecting against the sun's rays.HOW TO TAKE IT? Take 2 softgels a day. CONTAIN: DeltaGold, Annato extract (Bixa orellana) standardized to 50% tocotrienols - Other ingredients: rice bran oil

Inositol Hexanicotinate (IHN) 90 Caps

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Quatrefolic Vitamin B9 - Folic Acidd 400 Mcg Per Day

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydrofolic acidd. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of? Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acidd, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acidd because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acidd, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acidd into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acidd are ingested over long periods. Indeed, long-term supplementation with standard folic acidd-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake. Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acidd because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acidd. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acidd. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acidd (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

Inositol Hexanicotinate 1500mg (IHN - Niacin) - Improved Vitamin B3 90 Capsules

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Iron Bisglycinate 60Caps During Pregnancy. Indeed, Women Of Reproductive Age

Iron Bisglycinate Supplement Our dietary supplement Iron Bisglycinate offers a simple way of increasing your iron intake. The body needs iron in order to function properly. This trace element participates in a number of mechanisms of action including the formation of new cells, hormones and neurotransmitters. What are the benefits associated with Iron Bisglycinate supplement? Iron Bisglycinate is formulated from a specific form of iron - iron reacted with glycine to form a chelate called ferrous bisglycinate. This has the advantage of being an anti-fatigue form of iron with excellent bioavailability due to its low molecular weight. It is thus easily absorbed by the gut, making it bioavailable within the body. In addition, ferrous bisglycinate is a stable form of iron. Having no ion charge, it does not interact with other nutrients in the digestive system and is therefore well-absorbed by the body. Iron also plays an essential role in enabling red blood cells to transport oxygen from the respiratory system to the body's tissues. This is why a lack of iron can be damaging to our health and why supplementation is sometimes necessary - particularly since serious iron deficiency can impair cognitive development and cause iron-deficiency anemia - a condition in which a lack of iron results in a reduction in red blood cells leading to poor oxygenation of the body. Why is iron supplementation important? Iron deficiency has been a significant public health issue for several years. The World Health Organisation (WHO) estimates that 1.3 billion people suffer from iron deficiency anemia. Of the many potential causes, the most common is inadequate intake, or poor absorption, of dietary iron. The body does not produce iron and it must therefore be provided by the diet: Iron is found mainly in animal-source foods, hence the need for vegetarians and vegans to find alternative sources.A lack of dietary iron is also common among women, particularly during pregnancy. Indeed, women of reproductive age have increased iron requirements because their levels are more subject to depletion. It is estimated that iron levels may fall by up to 25% during menstruation and pregnancy.Iron deficiency may be caused by other factors such as intestinal malabsorption, gastrointestinal bleeding or gastric surgery.Inadequate iron intake resulting in deficiency can lead to health complications. Symptoms include: fatigue; muscle weakness; lack of stamina; light-headedness; loss of libido; sluggish immune system.These symptoms are associated with poor oxygenation of the body, both in muscles and in several organs such as the brain, heart, kidneys and lungs.Scientists have also observed that a lack of iron can lead to learning difficulties and poor concentration. This is why supplementing with iron may help improve cognitive ability and prevent heart failure. The ferrous bisglycinate used in our supplement is a safer, more effective form than either ferrous sulfate, iron citrate or iron D-gluconate, all of which can produce side-effects such as gastric problems. Studies on ferrous bisglycinate, on the other hand, have revealed no negative side-effects on the stomach wall or intestines. The benefits of this type of iron are now available to buy at Supersmart as a dietary supplement in the form of 25g capsules, with a suggested dose of three capsules a day for optimal iron intake. Buy Iron Bisglycinate to improve your iron intake.Key FeaturesHelps with anemia and iron deficiency.A lack of dietary iron is also common among women, particularly during pregnancy. Indeed, women of reproductive age have increased iron requirements because their levels are more subject to depletion. It is estimated that iron levels may fall by up to 25% during menstruation and pregnancy.Iron deficiency may be caused by other factors such as intestinal malabsorption, gastrointestinal bleeding or gastric surgery.Associated with improvements in cognitive ability.Meets the increased needs of iron for vegetariansIron is found mainly in animal-source foods, hence the need for vegetarians and vegans to find alternative sources.

Inositol Hexanicotinate Is A Form Of Niacin 90 Cap

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Inositol Hexanicotinate (IHN) 90 Capsules

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Astragalus Root Extract 100mg 60 Capsules

Astragaloside IV Supplement - Astragalus Extract with Anti-Ageing Properties Astragaloside IV is an anti-ageing supplement in vegetarian capsules with several beneficial properties, particularly immunostimulant, anti-inflammatory, antioxidant and anti-glycation. Its exceptional properties are due to astragaloside's specific ability to activate telomerase, thus slowing down the shortening of telomeres, and extending cell lifespan. Shortening of telomeres is associated with cellular ageing and the development of age-related diseases. How is Astragaloside IV obtained? Astragaloside IV is present in minute amounts in the root of Astragalus (Astragalus membranaceus), a plant particularly valued in traditional Chinese medicine. Through a highly complex and expensive process, it is extracted and concentrated in order to obtain an active amount. Commercially available products sold in the form of powder or astragalus extract do not contain detectable amounts of Astragaloside IV. Astragalus root has been prescribed for centuries as a tonic, as well as to treat a wide range of diseases, to prevent weakness in patients and to protect them against infection. What are the benefits associated with Astragaloside IV capsules? Astragalus root contains, amongst others, a series of cycloartane glycosides called astragalosides I to VII. The most widely studied of these, in Chinese and European research centres, is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV have the following properties: Immunostimulant: acting through a number of different pathways, especially by increasing the number of stem cells in the spinal cord and lymphatic tissue and encouraging them to develop into active immune cells and by stimulating the production of immunoglobulins and macrophages;Anti-inflammatory: as shown in certain animal models. The ability of astragaloside IV to stem inflammation of the airways in chronic asthma has been reported in studies on mice.Antibacterial: as demonstrated by in vitro studies on Shigella dysenteriae, Streptococcus haemolyticus, Diplococcus pneumoniae and Staphylococcus aureus.Antiviral: inhibiting replication of certain viruses such as coxsackie, responsible for myocarditis (inflammation of the heart muscle). In both animal and human studies, they were shown to stimulate endogenous interferon production and to maximise its effect on viral infections.Antioxidant: inhibiting lipid peroxidation by 40% in vitro. These antioxidant properties may go some way to explaining the cardio- and neuroprotective effects of astragalus and astragaloside IV.Cardioprotective: with studies highlighting health benefits for patients with congestive cardiac insufficiency and angina pectoris. Astragalus extracts have a cardiotonic effect.Neuroprotective: in traditional Chinese medicine, astragalus root extract is used to treat neurodegenerative diseases. One study demonstrated the capacity of astragaloside IV to protect dopaminergic neurons (progressive degeneration of dopaminergic neurons leads to the development of Parkinson's disease). Telomere shortening is currently one of the most widely studied areas of anti-ageing medicine. Along with astragaloside IV, there's a number of natural active principles available to buy at Supersmart, that have been identified for their ability to protect telomeres or stimulate telomerase. Two such ingredients are cycloastragenol and resveratrol. Other beneficial compounds, such as vitamins C and E, carnosine and several natural antioxidants, have also been included in the enhanced formulation Telomeres Maintenance Formula. The shortest telomeres have been observed in octogenarians. Research also suggests that individuals aged 60 or older with the shortest telomers appear to be at significantly higher risk of death from infectious disease or heart attacks. Conversely, studies have shown that stimulating telomerase may significantly increase cell lifespan. Buy Astragaloside IV to fight cellular ageing.Key FeaturesHas antioxidant, immune-stimulant and anti-inflammatory properties.Recognised for its specific ability to activate telomerase, slowing down the shortening of telomeres, and extending cell lifespan.Fights cellular ageing and the development of age-related diseases. WHAT IS IT? Astragaloside IV may be an anti-aging supplement in vegetarian capsules with several beneficial properties (immunostimulant, anti-inflammatory, antioxidant) due to astragaloside's specific ability to activate telomerase. WHAT ARE THE BENEFITS? The most widely studied in Chinese and European research centers is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV may have the properties to be an immunostimulant, anti-inflammatory, antioxidant. HOW TO TAKE IT? Take 2 capules a day. CONTAIN: Astragaloside IV 98% - Other ingredients : Acacia gum, rice flour.

Astragalus Root Extract 100mg 60Capsu

Astragaloside IV Supplement - Astragalus Extract with Anti-Ageing Properties Astragaloside IV is an anti-ageing supplement in vegetarian capsules with several beneficial properties, particularly immunostimulant, anti-inflammatory, antioxidant and anti-glycation. Its exceptional properties are due to astragaloside's specific ability to activate telomerase, thus slowing down the shortening of telomeres, and extending cell lifespan. Shortening of telomeres is associated with cellular ageing and the development of age-related diseases. How is Astragaloside IV obtained? Astragaloside IV is present in minute amounts in the root of Astragalus (Astragalus membranaceus), a plant particularly valued in traditional Chinese medicine. Through a highly complex and expensive process, it is extracted and concentrated in order to obtain an active amount. Commercially available products sold in the form of powder or astragalus extract do not contain detectable amounts of Astragaloside IV. Astragalus root has been prescribed for centuries as a tonic, as well as to treat a wide range of diseases, to prevent weakness in patients and to protect them against infection. What are the benefits associated with Astragaloside IV capsules? Astragalus root contains, amongst others, a series of cycloartane glycosides called astragalosides I to VII. The most widely studied of these, in Chinese and European research centres, is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV have the following properties: Immunostimulant: acting through a number of different pathways, especially by increasing the number of stem cells in the spinal cord and lymphatic tissue and encouraging them to develop into active immune cells and by stimulating the production of immunoglobulins and macrophages;Anti-inflammatory: as shown in certain animal models. The ability of astragaloside IV to stem inflammation of the airways in chronic asthma has been reported in studies on mice.Antibacterial: as demonstrated by in vitro studies on Shigella dysenteriae, Streptococcus haemolyticus, Diplococcus pneumoniae and Staphylococcus aureus.Antiviral: inhibiting replication of certain viruses such as coxsackie, responsible for myocarditis (inflammation of the heart muscle). In both animal and human studies, they were shown to stimulate endogenous interferon production and to maximise its effect on viral infections.Antioxidant: inhibiting lipid peroxidation by 40% in vitro. These antioxidant properties may go some way to explaining the cardio- and neuroprotective effects of astragalus and astragaloside IV.Cardioprotective: with studies highlighting health benefits for patients with congestive cardiac insufficiency and angina pectoris. Astragalus extracts have a cardiotonic effect.Neuroprotective: in traditional Chinese medicine, astragalus root extract is used to treat neurodegenerative diseases. One study demonstrated the capacity of astragaloside IV to protect dopaminergic neurons (progressive degeneration of dopaminergic neurons leads to the development of Parkinson's disease). Telomere shortening is currently one of the most widely studied areas of anti-ageing medicine. Along with astragaloside IV, there's a number of natural active principles available to buy at Supersmart, that have been identified for their ability to protect telomeres or stimulate telomerase. Two such ingredients are cycloastragenol and resveratrol. Other beneficial compounds, such as vitamins C and E, carnosine and several natural antioxidants, have also been included in the enhanced formulation Telomeres Maintenance Formula. The shortest telomeres have been observed in octogenarians. Research also suggests that individuals aged 60 or older with the shortest telomers appear to be at significantly higher risk of death from infectious disease or heart attacks. Conversely, studies have shown that stimulating telomerase may significantly increase cell lifespan. Buy Astragaloside IV to fight cellular ageing.Key FeaturesHas antioxidant, immune-stimulant and anti-inflammatory properties.Recognised for its specific ability to activate telomerase, slowing down the shortening of telomeres, and extending cell lifespan.Fights cellular ageing and the development of age-related diseases. WHAT IS IT? Astragaloside IV may be an anti-aging supplement in vegetarian capsules with several beneficial properties (immunostimulant, anti-inflammatory, antioxidant) due to astragaloside's specific ability to activate telomerase. WHAT ARE THE BENEFITS? The most widely studied in Chinese and European research centers is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV may have the properties to be an immunostimulant, anti-inflammatory, antioxidant. HOW TO TAKE IT? Take 2 capules a day. CONTAIN: Astragaloside IV 98% - Other ingredients : Acacia gum, rice flour.

Vitamin E Tocotrienols.Annatto Tocotrienols 60 Softgel

Our Annatto Tocotrienols supplement is formulated from an extract of Bixa orellana. Also known as roucou, urucum, achiote, and simply annattos, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for several health benefits. These seed-filled fruits have been used for many years in traditional medicine, where they have mostly been used for insect bites and protecting the skin against the sun's rays. But Bixa Orellana fruits offer considerably more benefits than that. They are rich in carotenoids, such as beta-carotene, a powerful natural antioxidant, and contain a number of trace elements, including selenium, magnesium, and calcium. They also have a high content of a specific form of Vitamin E called tocotrienols, so it also works as a healthy natural Vitamin E supplement. Annatto Tocotrienols Benefits Given its essential role in the body, Vitamin E must be ingested in sufficient amounts. While it is present in plants, such as vegetable oils and nuts, it can be easy not to get enough of it. In fact, there is not just one form of Vitamin E, but eight, that are grouped into tocopherols and tocotrienols. There are fewer dietary sources of tocotrienols, specifically, which is why our Annatto Tocotrienols supplement has been formulated from natural tocotrienols extracted from the fruit of Bixa orellana. Our formulation offers 90% delta-tocotrienols and 10% gamma-tocotrienols. Like all vitamins, Vitamin E has a number of roles within the body. It also has many properties in common with other vitamins, such as natural antioxidant power, which it shares with its well-known counterpart, Vitamin C. Annatto Tocotrienols benefits may include: Fighting aging of the cells and skin by protecting cell membranes, such as those in the skin.Combating coronary disease, a type of cardiovascular disease caused by circulation problems, by protecting the red blood cells responsible for healthy oxygenation of the body.Combating the onset of cardiovascular events, such as heart attacks and strokes, by protecting low-density lipoproteins (LDLs) — particles known for their key role in transporting cholesterol in the bloodstream. What does research show about Bixa Orellana Seed Extract? Despite the many studies conducted on tocotrienols, their mechanism of action within the body has yet to be fully explained. Research suggests, however, that these forms of natural Vitamin E may offer significant therapeutic potential. In fact, studies show that tocotrienols may: Positively influence cholesterol metabolism due to an inhibitory effect on the enzyme HMG-CoA, which reduces the amount of cholesterol produced by the liver.Potentially reduce levels of bad LDL-cholesterol and increase levels of good HDL-cholesterol.Promote a balanced lipid profile, helping to combat the build-up of atheromatous plaque in the arteries and maintain normal blood levels of glucose and triglycerides.Have a diuretic effect — i.e. promote the production of urine.Combat the risk of developing a Vitamin E deficiency. In essence, Bixa Orellana seed extract offers significant therapeutic potential. In order to create a high-quality supplement, Annatto Tocotrienols has been formulated from natural extracts and is produced in the form of softgels. Each capsule contains 100 mg of annatto extract (Bixa Orellana) standardized to 50% tocotrienols. In addition to this natural tocotrienols supplement, you can buy our Gamma E Tocopherols product to increase intake of other forms of Vitamin E. Annatto Tocotrienols Side Effects Are Annatto Tocotrienols supplements safe to consume? Taking Annatto capsules from the Roucou plant is generally safe for anyone looking to improve their overall health. Annatto or Vitamin E will rarely lead to side effects, but it is always important to research all the pros and cons in order to ensure it's good for your own well being. Most instances of side effects acquired through taking a supplement containing Bixa Orellana occur due to not following the recommended serving size. Side effects from supplements are always more likely when taking too much, and exceeding the serving size won't enhance the effects. If you are taking any existing prescription medications for chronic illnesses, it is strongly recommended to schedule a visit to your doctor. They will be able to analyze your medical history to determine whether Annatto Tocotrienols will cause any adverse drug interactions. You will find plenty of online research materials relating to Annatto extract, the Achiote plant, and Bixa Orellana seed extract that detail potential side effects and any other associated risks. Some people also like to speak to others about their experiences with Annatto Tocotrienols' side effects. Consulting with others — either in real life or online via forums — will give you a better idea of the benefits and drawbacks of adding this supplement to your daily regimen. When taking any supplement, carefully monitor the effects on your mind and body. If you experience any side effects, stop taking your Annatto supplement immediately and consult your doctor. It is common for people taking prescription medications and other supplements to experience adverse side effects. Speaking to your primary care physician can shed light on why it may be happening and how to take an Annatto Vitamin E supplement safely. Take control of your health and always consume dietary supplements responsibly.Key FeaturesHas a high content of a specific form of Vitamin E called tocotrienols.Supports healthy cholesterol metabolism.Powerful natural antioxidant.WHAT IS IT? Our dietary supplement Annatto Tocotrienols is formulated from an extract of Bixa orellana. Also known as roucou, urucum and achiote, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for their health benefits. WHY TAKE IT? Known as annattos, these seed-filled fruits have been used for many years in traditional medicine, where they may be recommended for treating insect bites or for protecting against the sun's rays.HOW TO TAKE IT? Take 2 softgels a day. CONTAIN: DeltaGold, Annato extract (Bixa orellana) standardized to 50% tocotrienols - Other ingredients: rice bran oil

Vitamin E Tocotrienols.Annatto Tocotrienols 60Softgel

Our Annatto Tocotrienols supplement is formulated from an extract of Bixa orellana. Also known as roucou, urucum, achiote, and simply annattos, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for several health benefits. These seed-filled fruits have been used for many years in traditional medicine, where they have mostly been used for insect bites and protecting the skin against the sun's rays. But Bixa Orellana fruits offer considerably more benefits than that. They are rich in carotenoids, such as beta-carotene, a powerful natural antioxidant, and contain a number of trace elements, including selenium, magnesium, and calcium. They also have a high content of a specific form of Vitamin E called tocotrienols, so it also works as a healthy natural Vitamin E supplement. Annatto Tocotrienols Benefits Given its essential role in the body, Vitamin E must be ingested in sufficient amounts. While it is present in plants, such as vegetable oils and nuts, it can be easy not to get enough of it. In fact, there is not just one form of Vitamin E, but eight, that are grouped into tocopherols and tocotrienols. There are fewer dietary sources of tocotrienols, specifically, which is why our Annatto Tocotrienols supplement has been formulated from natural tocotrienols extracted from the fruit of Bixa orellana. Our formulation offers 90% delta-tocotrienols and 10% gamma-tocotrienols. Like all vitamins, Vitamin E has a number of roles within the body. It also has many properties in common with other vitamins, such as natural antioxidant power, which it shares with its well-known counterpart, Vitamin C. Annatto Tocotrienols benefits may include: Fighting aging of the cells and skin by protecting cell membranes, such as those in the skin.Combating coronary disease, a type of cardiovascular disease caused by circulation problems, by protecting the red blood cells responsible for healthy oxygenation of the body.Combating the onset of cardiovascular events, such as heart attacks and strokes, by protecting low-density lipoproteins (LDLs) — particles known for their key role in transporting cholesterol in the bloodstream. What does research show about Bixa Orellana Seed Extract? Despite the many studies conducted on tocotrienols, their mechanism of action within the body has yet to be fully explained. Research suggests, however, that these forms of natural Vitamin E may offer significant therapeutic potential. In fact, studies show that tocotrienols may: Positively influence cholesterol metabolism due to an inhibitory effect on the enzyme HMG-CoA, which reduces the amount of cholesterol produced by the liver.Potentially reduce levels of bad LDL-cholesterol and increase levels of good HDL-cholesterol.Promote a balanced lipid profile, helping to combat the build-up of atheromatous plaque in the arteries and maintain normal blood levels of glucose and triglycerides.Have a diuretic effect — i.e. promote the production of urine.Combat the risk of developing a Vitamin E deficiency. In essence, Bixa Orellana seed extract offers significant therapeutic potential. In order to create a high-quality supplement, Annatto Tocotrienols has been formulated from natural extracts and is produced in the form of softgels. Each capsule contains 100 mg of annatto extract (Bixa Orellana) standardized to 50% tocotrienols. In addition to this natural tocotrienols supplement, you can buy our Gamma E Tocopherols product to increase intake of other forms of Vitamin E. Annatto Tocotrienols Side Effects Are Annatto Tocotrienols supplements safe to consume? Taking Annatto capsules from the Roucou plant is generally safe for anyone looking to improve their overall health. Annatto or Vitamin E will rarely lead to side effects, but it is always important to research all the pros and cons in order to ensure it's good for your own well being. Most instances of side effects acquired through taking a supplement containing Bixa Orellana occur due to not following the recommended serving size. Side effects from supplements are always more likely when taking too much, and exceeding the serving size won't enhance the effects. If you are taking any existing prescription medications for chronic illnesses, it is strongly recommended to schedule a visit to your doctor. They will be able to analyze your medical history to determine whether Annatto Tocotrienols will cause any adverse drug interactions. You will find plenty of online research materials relating to Annatto extract, the Achiote plant, and Bixa Orellana seed extract that detail potential side effects and any other associated risks. Some people also like to speak to others about their experiences with Annatto Tocotrienols' side effects. Consulting with others — either in real life or online via forums — will give you a better idea of the benefits and drawbacks of adding this supplement to your daily regimen. When taking any supplement, carefully monitor the effects on your mind and body. If you experience any side effects, stop taking your Annatto supplement immediately and consult your doctor. It is common for people taking prescription medications and other supplements to experience adverse side effects. Speaking to your primary care physician can shed light on why it may be happening and how to take an Annatto Vitamin E supplement safely. Take control of your health and always consume dietary supplements responsibly.Key FeaturesHas a high content of a specific form of Vitamin E called tocotrienols.Supports healthy cholesterol metabolism.Powerful natural antioxidant.WHAT IS IT? Our dietary supplement Annatto Tocotrienols is formulated from an extract of Bixa orellana. Also known as roucou, urucum and achiote, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for their health benefits. WHY TAKE IT? Known as annattos, these seed-filled fruits have been used for many years in traditional medicine, where they may be recommended for treating insect bites or for protecting against the sun's rays.HOW TO TAKE IT? Take 2 softgels a day. CONTAIN: DeltaGold, Annato extract (Bixa orellana) standardized to 50% tocotrienols - Other ingredients: rice bran oil

Conntrated Vitamin B9 - Folic Acidd 400 Mcg 120 Tablet

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydrofolic acidd. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of? Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acidd, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acidd because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acidd, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acidd into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acidd are ingested over long periods. Indeed, long-term supplementation with standard folic acidd-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake. Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acidd because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acidd. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acidd. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acidd (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

Astragaloside IV 98% 100mg 60Caps

Astragaloside IV Supplement - Astragalus Extract with Anti-Ageing Properties Astragaloside IV is an anti-ageing supplement in vegetarian capsules with several beneficial properties, particularly immunostimulant, anti-inflammatory, antioxidant and anti-glycation. Its exceptional properties are due to astragaloside's specific ability to activate telomerase, thus slowing down the shortening of telomeres, and extending cell lifespan. Shortening of telomeres is associated with cellular ageing and the development of age-related diseases. How is Astragaloside IV obtained? Astragaloside IV is present in minute amounts in the root of Astragalus (Astragalus membranaceus), a plant particularly valued in traditional Chinese medicine. Through a highly complex and expensive process, it is extracted and concentrated in order to obtain an active amount. Commercially available products sold in the form of powder or astragalus extract do not contain detectable amounts of Astragaloside IV. Astragalus root has been prescribed for centuries as a tonic, as well as to treat a wide range of diseases, to prevent weakness in patients and to protect them against infection. What are the benefits associated with Astragaloside IV capsules? Astragalus root contains, amongst others, a series of cycloartane glycosides called astragalosides I to VII. The most widely studied of these, in Chinese and European research centres, is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV have the following properties: Immunostimulant: acting through a number of different pathways, especially by increasing the number of stem cells in the spinal cord and lymphatic tissue and encouraging them to develop into active immune cells and by stimulating the production of immunoglobulins and macrophages;Anti-inflammatory: as shown in certain animal models. The ability of astragaloside IV to stem inflammation of the airways in chronic asthma has been reported in studies on mice.Antibacterial: as demonstrated by in vitro studies on Shigella dysenteriae, Streptococcus haemolyticus, Diplococcus pneumoniae and Staphylococcus aureus.Antiviral: inhibiting replication of certain viruses such as coxsackie, responsible for myocarditis (inflammation of the heart muscle). In both animal and human studies, they were shown to stimulate endogenous interferon production and to maximise its effect on viral infections.Antioxidant: inhibiting lipid peroxidation by 40% in vitro. These antioxidant properties may go some way to explaining the cardio- and neuroprotective effects of astragalus and astragaloside IV.Cardioprotective: with studies highlighting health benefits for patients with congestive cardiac insufficiency and angina pectoris. Astragalus extracts have a cardiotonic effect.Neuroprotective: in traditional Chinese medicine, astragalus root extract is used to treat neurodegenerative diseases. One study demonstrated the capacity of astragaloside IV to protect dopaminergic neurons (progressive degeneration of dopaminergic neurons leads to the development of Parkinson's disease). Telomere shortening is currently one of the most widely studied areas of anti-ageing medicine. Along with astragaloside IV, there's a number of natural active principles available to buy at Supersmart, that have been identified for their ability to protect telomeres or stimulate telomerase. Two such ingredients are cycloastragenol and resveratrol. Other beneficial compounds, such as vitamins C and E, carnosine and several natural antioxidants, have also been included in the enhanced formulation Telomeres Maintenance Formula. The shortest telomeres have been observed in octogenarians. Research also suggests that individuals aged 60 or older with the shortest telomers appear to be at significantly higher risk of death from infectious disease or heart attacks. Conversely, studies have shown that stimulating telomerase may significantly increase cell lifespan. Buy Astragaloside IV to fight cellular ageing.Key FeaturesHas antioxidant, immune-stimulant and anti-inflammatory properties.Recognised for its specific ability to activate telomerase, slowing down the shortening of telomeres, and extending cell lifespan.Fights cellular ageing and the development of age-related diseases. WHAT IS IT? Astragaloside IV may be an anti-aging supplement in vegetarian capsules with several beneficial properties (immunostimulant, anti-inflammatory, antioxidant) due to astragaloside's specific ability to activate telomerase. WHAT ARE THE BENEFITS? The most widely studied in Chinese and European research centers is astragaloside IV. Studies suggest, amongst others, that astragalus root extract and astragaloside IV may have the properties to be an immunostimulant, anti-inflammatory, antioxidant. HOW TO TAKE IT? Take 2 capules a day. CONTAIN: Astragaloside IV 98% - Other ingredients : Acacia gum, rice flour.

Inositol Hexanicotinate 1500mg (IHN - Niacin) Improved Vitamin B3 90Caps

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Pyrroloquinoline Quinone (PQQ) And Co-enzyme Q10 (CoQ10) 30 Caps

This PQQ & CoQ10 supplement improves antioxidant status and mitochondrial health via complementary mechanisms by providing multi-faceted support for cardiovascular and cerebral function. It also improves mental condition and quality of life in elderly patients and may be beneficial in delaying or preventing cognitive decline in middle-aged individuals. What are the benefits associated with PQQ & Q10 capsules? This new dietary supplement offers the synergistic benefits of pyrroloquinoline quinone (PQQ) and co-enzyme Q10 (CoQ10). Extensively studied in recent years, these two compounds offer significant antioxidant potency. They are thus able to combat oxidative stress - the result of attacks on cells by highly reactive species. The best-known of these are free radicals which contribute to premature aging of cells as well as the development of certain age-related disorders such as cognitive impairment. The good news is that antioxidants are available which can fight the effects of free radicals and protect cognitive function, such as PQQ and CoQ10. PQQ PQQ - or to give it its scientific name, pyrroloquinoline quinone - is one of the most powerful antioxidants currently known. It has the advantage of having good molecular stability which makes it highly effective at fighting oxidative stress. Its antioxidant activity is particularly beneficial for protecting mitochondria, the cell structures essential for energy production. In addition to this protective role, it promotes new mitochondrial growth: It's an ultra-powerful antioxidant, up to 5,000 times more effective than vitamin C.It's the only nutrient capable of generating new mitochondria - up to 20% more, in existing - even aging - cells.It uniquely ensures protection for mitochondrial DNA, which is particularly exposed and vulnerable to oxidative stress. Coenzyme Q10 Coenzyme Q10 features in the composition of a number of anti-aging formulations. In helping to protect the body against free radicals, coenzyme Q10 helps prevent premature aging of the cells and the onset of certain age-related symptoms. In addition, this powerful antioxidant works within the mitochondria for the production of adenosine triphosphate (ATP). The main energy source for numerous cellular functions, ATP is essential in order for the body to function properly. Despite this critical role, the body's ATP reserves are very low and need to be constantly renewed, hence the importance of coenzyme Q10 for maintaining vital and cognitive functions. Why combine PQQ and Q10? Often recommended individually, PQQ and CoQ10 are combined in this supplement to take advantage of their synergistic effects. Indeed, recent research has shown that combining them in this way may strengthen their protective role against oxidative stress. These studies suggest that their antioxidant effects may be particularly enhanced in the cardiovascular and nervous systems. As a result, PQQ and CoQ10 are today associated with protecting the heart, red blood cells and brain, as well as preventing age-related problems such as memory loss and concentration deficit. The suggested dose for this PQQ & CoQ10 supplement is two capsules a day. Other powerful antioxidants are also available at Supersmart for fighting age-related cellular damage such as resveratrol, the natural antioxidant found in grapes and red wine. For optimal efficacy, this protective compound can also be combined with other antioxidants such as in the synergistic formulation Resveratrol Synergy. Buy PQQ & Q10 to help fight cellular aging.Key FeaturesProtects against the oxidative stress responsible for aging.May fight age-related decline in cognitive function (attention, memory).Contains key nutrients for protecting the heart, brain and red blood cells.THIS PQQ AND COQ10 supplement improves antioxidant status and mitochondrial health via complementary mechanismsWHAT ARE THE BENEFITS? It provides multi-faceted support for cardiovascular and cerebral function. It also improves mental condition and quality of life in elderly patients and may be beneficial in delaying or preventing cognitive decline in middle-aged individualsHOW TO TAKE IT? Take 1 or 2 capsules a day, preferably with a meal containing a little fat.CONTAIN: Pyrroloquinoline quinone, Coenzyme Q10. Other ingredients : Acacia Gum.

Super Folate Folic Acid 400Mcg Per Day

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydrofolic acid. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of? Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acid, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acid because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acid, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acid into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acid are ingested over long periods. Indeed, long-term supplementation with standard folic acid-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake. Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acid because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acid. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acid. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acid (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

Inositol Hexanicotinate Is A Form Of Niacin, An Essential B Vitamin 90 Capsules

Inositol hexanicotinate or IHN (six molecules of niacin bound to a single molecule of inositol) is the only form of niacin which causes neither redness nor flushes, thus providing all the benefits of higher-dose niacin (500 mg per vegicap) without the flush', now available to buy in vegetarian capsules at Supersmart. IHN is mainly recommended for lowering LDL cholesterol and raising HDL cholesterol, for reducing triglycerides and as a vasodilator, particularly for peripheral circulation problems. Healthy individuals also take lower doses of IHN for prevention purposes and for the many metabolic benefits associated with niacin supplementation. Why take Inositol Hexanicotinate? Niacin is an essential B vitamin which plays a key role in cerebral and cardiovascular health and which is involved in a multitude of cellular and enzymatic processes. One of niacin's functions in the body is to help eliminate bad' LDL cholesterol and increase good' HDL cholesterol. Its ability to do so has been demonstrated in numerous studies: niacin is the only nutrient to produce a 30% or more increase in HDL, a significant improvement in a key marker of cardiovascular health. Such is the effectiveness of niacin in controlling cholesterol levels, reducing levels of lipoprotein (a) and controlling dyslipidaemia that it has long been used in conventional medicine, despite its extraordinary, if harmless, side-effects (the famous niacin flush', the result of peripheral vasodilation which makes the skin go red a few minutes after taking it). Niacin subsequently gave way to drugs such as statins, which though not totally problem-free when used long-term, had a side-effect profile that was perhaps more commercially-acceptable. Buy Inositol Hexanicotinate capsules to help lower LDL cholesterol and raise HDL cholesterol.Key FeaturesHelps to lower LDL cholesterol and raise HDL cholesterol.Aids in reducing triglycerides and acts as a vasodilator for peripheral circulation problems.Only form of niacin that doesn't cause redness or flushes.NIACIN AN ESSENTIAL B3 VITAMIN which plays a key role in cerebral and cardiovascular health. Helps eliminate bad LDL cholesterol and increase good HDL cholesterolWHAT PURPOSE? Supports healthy liver function, membrane function, and overall reproduction health. Great for the nervous system, fertilization, and cognitive focusHOW TO TAKE IT? Take 1-3 vegetarian capsules a day after food, or up to 6 as advised by your therapist.CONTAIN: Inositol hexanicotinate - Other ingredients: Acacia Gum, Rice Bran.

Iron Bisglycinate 60 Caps During Pregnancy. Indeed, Women Of Reproductive Age

Calcium orotate is an exceptional calcium supplement designed to consolidate the skeleton. In the short term, it also helps normalise the nervous system and cardiovascular function. Its orotate form maximises its absorption and thus its efficacy. Why take calcium in supplement form? Of all the nutrients important for bone health, calcium is the most extensively-researched. Several studies have identified a correlation between increased intake of calcium and consolidation of bone mass. This mineral constitutes almost 2% of body weight, and is primarily concentrated in the bones and teeth. Long-term benefits: it helps maintain the skeleton and reduce bone loss. Short-term benefits: calcium also plays a key role in ensuring normal function of heart and nerve cells. It plays a role in hundreds of enzymatic processes involved in various physiological functions. What is an orotate? What benefit does it offer? Orotates are mineral salts of orotic acid, a natural substance present in the body and also found in several foods. Calcium is always sold in the form of salts (citrate, malate, carbonate, lactate, gluconate, orotate …) but the quality of this salt can be crucial to the supplement's efficacy. Calcium carbonate supplements are the most commonly-available products, and the cheapest, but they are poorly absorbed by those with lower-than-average levels of gastric acid, which is unfortunately the case for most people over 60. They can also cause constipation problems. Of all the supplements available, those in which the calcium is bound to an organic acid, such as calcium orotate, definitely offer the best rates of absorption, usually over 40%. They are more expensive but they deliver the calcium right to the cell nucleus, enabling optimal mineralisation. Who should supplement with calcium orotate? Everyone can benefit from supplementing with calcium but the following population groups may find it particularly useful: Those over 40 (this is the age at which bone mass starts to decline, by around 1%-2% a year).Menopausal women (in the decade following the onset of the menopause, bone loss accelerates by 2%-3% a year due to the decline in oestrogen production).Those with a family history of osteoporosis-induced fractures.Women who do little or no exercise.Those suffering from inflammatory bowel diseases (like Crohn's). How should you take Calcium Orotate ?his two-fold process enables the body to remain in tune with its environment. Damaged bone is rapidly re-made and the body can even build stronger bones if the environmental conditions change (new physical activity, for example). However, it's important for this dual process to remain in balance. If the resorption phase takes over or if the building blocks - such as calcium - are missing, the depressions are never filled in and the bones become dangerously fragile. This is exactly what happens with osteoporosis. Why does the formulation contain magnesium? Although magnesium is a minor constituent of bone, it is essential for vitamin D synthesis and the action of parathyroid hormone (PTH) (1-2). This facilitates active absorption of the calcium present in the digestive tract and assists in its resorption by bones. In other words, vitamin D cannot be used correctly by the body if magnesium levels are too low. The small amount of vitamin D circulating in the body (produced on exposure of the skin to the sun's rays, or provided by the diet or supplements) is under-exploited. Magnesium is therefore vital for maintaining balance in the bones: any lasting shortfall is associated with osteoporosis and bone fragility. The latest research findings on calcium A high-salt diet plays a role in depleting calcium stores as sodium takes calcium with it when it is eliminated from the body in urine (2012) (3). What has more of an effect on bone strength and resistance - nutrition or exercise? A team from the University of Michigan has concluded that it's nutrition, though the two factors together are even more impactful (2018) (4). Notes This product should not be seen as a replacement for a varied, balanced diet or healthy lifestyle. Follow the recommendations for use and the daily dose and observe the use-by date. Not recommended for women who are pregnant or breastfeeding, or for children under 15. Keep out of young children's reach. Store in a cool, dry placeKey FeaturesHelps with anemia and iron deficiency.A lack of dietary iron is also common among women, particularly during pregnancy. Indeed, women of reproductive age have increased iron requirements because their levels are more subject to depletion. It is estimated that iron levels may fall by up to 25% during menstruation and pregnancy.Iron deficiency may be caused by other factors such as intestinal malabsorption, gastrointestinal bleeding or gastric surgery.Associated with improvements in cognitive ability.Meets the increased needs of iron for vegetariansIron is found mainly in animal-source foods, hence the need for vegetarians and vegans to find alternative sources.

SuperFolate 400 Mcg 120Tablets Folic Acid

SuperFolate is a highly bioavailable vitamin B9 supplement. Active form, immediately available to use by cells.Voted 'Product of the Year' at the NutraIngredients Award 2016.Recommended during pregnancy to ensure healthy fetal development.Contributes to the normal functioning of the immune system and normal psychological function.Contributes to normal blood formation and reduces fatigue.SuperFolate Supplement -Vitamin B9 to Help with Healthy Fetal DevelopmentSuperFolate consists of a new form of vitamin B9, Quatrefolic®, providing (6S) 5-methyltetrahydrofolic acid. Studies have highlighted its key role in cell growth, DNA synthesis and red blood cell formation. What is SuperFolate composed of? Quatrefolic® is a form of vitamin B9 with excellent bioavailability which does not produce elevated levels of unmetabolised folic acid, the long-term effects of which have yet to be determined. In March 2014, the European Commission approved this new form of vitamin B9 as a Novel Food Ingredient for use in dietary supplements following the EFSA's favourable opinion delivered in October 2013, and DFA approval of Quatrefolic® as a New Dietary Ingredient in 2010. Quatrefolic® - the fourth-generation folate - offers improved water-solubility as well as optimal bioavailability compared with other forms of folic acid because it does not have to be metabolically converted and is thus immediately available for use by cells. Neither does it produce increased levels of unmetabolised folic acid, the potential long-term effects of which are still the subject of scientific debate and is therefore completely safe. The conversion of folic acid into 5-methyltetrahydrofolate is mediated by the action of enzymes but these can become saturated when high levels of folic acid are ingested over long periods. Indeed, long-term supplementation with standard folic acid-based products may accelerate the development of cancer in people with pre-cancerous lesions or tumours. SuperFolate, therefore, represents a completely safe form of vitamin B9 with all the known properties of folates naturally present in the diet. What are the benefits associated with SuperFolate? The importance of B9 is well-established - the vitamin has been widely studied in young women and mothers-to-be in order to ensure healthy fetal development and reduce the risk of neural tube defects. Lack of vitamin B9 is recognised to be among the most common deficiencies and it is vital to ensure women of reproductive age have a regular and adequate intake. Like methionine, folates are key elements in the DNA methylation cycle, also known as one-carbon metabolism, which is essential for normal cell function. Folates thus act as major coenzymes in the transfer of monocarbonated groups (CH3). They help protect against genetic aberrations which may lead to the development of cancer, and also help the body synthesise proteins which destroy cancerous cells. There is now conclusive proof that deficiency in folates and vitamin B12 affects methylation processes. Combined with vitamin B12, folates also ensure that homocysteine is converted into methionine, which is essential for healthy cardiovascular function. It is, therefore, better to supplement with 5-methyltetrahydrofolate than folic acid because the former is available immediately to react with homocysteine and thus prevent hyperhomocysteinemia. Supplementing with SuperFolate will thus have benefits for: Cardiovascular disease.Colon cancer and polyps, as demonstrated in numerous epidemiological studies.End-stage renal failure.Diabetic neuropathy.Problems of the central nervous system such as cognitive impairment, age-related memory loss and depression, due to improved transport across the blood-brain barrier. SuperFolate is, therefore, the most active and safest form of vitamin B9, now available to buy at Supersmart. Each SuperFolate tablet contains 370mcg of Quatrefolic® providing 200 mcg of (6S)-5-methyltetrahydrofolic acid. Taking two tablets a day with meals can provide a powerful defence against various age-related diseases. Buy SuperFolate for a safe intake of vitamin B9.Key FeaturesWhat is it? Quatrefolic is a form of vitamin B9 with excellent bioavailability that does not produce increased amounts of non-metabolised folic acid. What are the benefits? Highly bioavailable vitamin B9 dietary supplement with improved bioeffectiveness. Studies have highlighted its key role for cell growth, DNA synthesis and the formation of red blood cells. Recommended use: take 2 tablets per day. Contains: (6S)-5-methyltetrahydrofolic acid (from 740 mg quatrefolic (6S)-5-methyltetrahydrofolic acid, glucosamine salt). Other ingredients: calcium carbonate, stearic acid, maltodextrin, sodium croscarmellose, shellac. Quatrefolic is a Registered trademark. by Gnosis S.p.A. U.S. Patent No. 7,947,642

Natural Active Form Of Vitamin E.Annatto Tocotrienols 60Softgel

Our Annatto Tocotrienols supplement is formulated from an extract of Bixa orellana. Also known as roucou, urucum, achiote, and simply annattos, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for several health benefits. These seed-filled fruits have been used for many years in traditional medicine, where they have mostly been used for insect bites and protecting the skin against the sun's rays. But Bixa Orellana fruits offer considerably more benefits than that. They are rich in carotenoids, such as beta-carotene, a powerful natural antioxidant, and contain a number of trace elements, including selenium, magnesium, and calcium. They also have a high content of a specific form of Vitamin E called tocotrienols, so it also works as a healthy natural Vitamin E supplement. Annatto Tocotrienols Benefits Given its essential role in the body, Vitamin E must be ingested in sufficient amounts. While it is present in plants, such as vegetable oils and nuts, it can be easy not to get enough of it. In fact, there is not just one form of Vitamin E, but eight, that are grouped into tocopherols and tocotrienols. There are fewer dietary sources of tocotrienols, specifically, which is why our Annatto Tocotrienols supplement has been formulated from natural tocotrienols extracted from the fruit of Bixa orellana. Our formulation offers 90% delta-tocotrienols and 10% gamma-tocotrienols. Like all vitamins, Vitamin E has a number of roles within the body. It also has many properties in common with other vitamins, such as natural antioxidant power, which it shares with its well-known counterpart, Vitamin C. Annatto Tocotrienols benefits may include: Fighting aging of the cells and skin by protecting cell membranes, such as those in the skin.Combating coronary disease, a type of cardiovascular disease caused by circulation problems, by protecting the red blood cells responsible for healthy oxygenation of the body.Combating the onset of cardiovascular events, such as heart attacks and strokes, by protecting low-density lipoproteins (LDLs) — particles known for their key role in transporting cholesterol in the bloodstream. What does research show about Bixa Orellana Seed Extract? Despite the many studies conducted on tocotrienols, their mechanism of action within the body has yet to be fully explained. Research suggests, however, that these forms of natural Vitamin E may offer significant therapeutic potential. In fact, studies show that tocotrienols may: Positively influence cholesterol metabolism due to an inhibitory effect on the enzyme HMG-CoA, which reduces the amount of cholesterol produced by the liver.Potentially reduce levels of bad LDL-cholesterol and increase levels of good HDL-cholesterol.Promote a balanced lipid profile, helping to combat the build-up of atheromatous plaque in the arteries and maintain normal blood levels of glucose and triglycerides.Have a diuretic effect — i.e. promote the production of urine.Combat the risk of developing a Vitamin E deficiency. In essence, Bixa Orellana seed extract offers significant therapeutic potential. In order to create a high-quality supplement, Annatto Tocotrienols has been formulated from natural extracts and is produced in the form of softgels. Each capsule contains 100 mg of annatto extract (Bixa Orellana) standardized to 50% tocotrienols. In addition to this natural tocotrienols supplement, you can buy our Gamma E Tocopherols product to increase intake of other forms of Vitamin E. Annatto Tocotrienols Side Effects Are Annatto Tocotrienols supplements safe to consume? Taking Annatto capsules from the Roucou plant is generally safe for anyone looking to improve their overall health. Annatto or Vitamin E will rarely lead to side effects, but it is always important to research all the pros and cons in order to ensure it's good for your own well being. Most instances of side effects acquired through taking a supplement containing Bixa Orellana occur due to not following the recommended serving size. Side effects from supplements are always more likely when taking too much, and exceeding the serving size won't enhance the effects. If you are taking any existing prescription medications for chronic illnesses, it is strongly recommended to schedule a visit to your doctor. They will be able to analyze your medical history to determine whether Annatto Tocotrienols will cause any adverse drug interactions. You will find plenty of online research materials relating to Annatto extract, the Achiote plant, and Bixa Orellana seed extract that detail potential side effects and any other associated risks. Some people also like to speak to others about their experiences with Annatto Tocotrienols' side effects. Consulting with others — either in real life or online via forums — will give you a better idea of the benefits and drawbacks of adding this supplement to your daily regimen. When taking any supplement, carefully monitor the effects on your mind and body. If you experience any side effects, stop taking your Annatto supplement immediately and consult your doctor. It is common for people taking prescription medications and other supplements to experience adverse side effects. Speaking to your primary care physician can shed light on why it may be happening and how to take an Annatto Vitamin E supplement safely. Take control of your health and always consume dietary supplements responsibly.Key FeaturesHas a high content of a specific form of Vitamin E called tocotrienols.Supports healthy cholesterol metabolism.Powerful natural antioxidant.WHAT IS IT? Our dietary supplement Annatto Tocotrienols is formulated from an extract of Bixa orellana. Also known as roucou, urucum and achiote, this shrub grows in tropical regions of the Americas, where its spiky red fruits are recognized for their health benefits. WHY TAKE IT? Known as annattos, these seed-filled fruits have been used for many years in traditional medicine, where they may be recommended for treating insect bites or for protecting against the sun's rays.HOW TO TAKE IT? Take 2 softgels a day. CONTAIN: DeltaGold, Annato extract (Bixa orellana) standardized to 50% tocotrienols - Other ingredients: rice bran oil