Caduet is used to treat high blood pressure (hypertension) or chest pain (angina), and to lower the risk of stroke, heart attack, and other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.
Caduet is used in adults and children who are at least 10 years old.
Warnings
You should not Caduet if you have liver disease.
Amlodipine and atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.
Do not breastfeed while taking Caduet.
Before taking Caduet, tell your doctor if you have ever had liver or kidney disease, heart disease, diabetes, or a thyroid disorder, or if you drink more than 2 alcoholic beverages daily.
In rare cases, Caduet can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).
Avoid eating foods that are high in fat or cholesterol. Caduet will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.
Some medicines can cause unwanted or dangerous effects when used with Caduet. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Caduet.
Before taking this medicine
You should not use Caduet if you are allergic to amlodipine (Norvasc) or atorvastatin (Lipitor), or if:
you have liver disease; or
you are pregnant or breastfeeding.
Do not use Caduet if you are pregnant. This medicine can harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine. If you become pregnant, stop taking this medicine and tell your doctor right away.
Do not breastfeed a baby while you are taking Caduet.
Tell your doctor if you have ever had:
kidney disease;
heart disease;
muscle pain or weakness;
diabetes;
a thyroid disorder; or
if you drink more than 2 alcoholic beverages daily.
Atorvastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).
Certain other drugs can increase your risk of serious muscle problems when used with Caduet. Your doctor may need to change your treatment plan if you use any of the following drugs:
colchicine;
cyclosporine;
medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
an antibiotic - clarithromycin, erythromycin;
antifungal medicine - itraconazole, ketoconazole, voriconazole;
certain cholesterol medications - gemfibrozil, fenofibric acid, fenofibrate; or
antiviral medicine to treat hepatitis C or HIV/AIDS - boceprevir, darunavir, fosamprenavir, lopinavir, nelfinavir, ritonavir, saquinavir, telaprevir, tipranavir.
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